What Are Polynucleotides — And Why Are People Calling It "Salmon Sperm Facial"?

If you’ve heard whispers about something called polynucleotides or the so-called salmon sperm facial, you’re not imagining things. Yes, it sounds odd — but it’s also one of the most exciting skin treatments on the aesthetics scene right now.

Let’s break it down.

So… what actually are polynucleotides?

Polynucleotides are tiny chains of DNA, usually derived from salmon (yep — that’s where the name comes from). Don’t worry though — they’re super purified, sterile, and totally safe for human use.

Their job? Regeneration. Think of them as skin whisperers that encourage your body to repair, renew, and rejuvenate itself from the inside out.

How do they work?

Polynucleotides trigger a natural healing response in your skin. They boost hydration, reduce inflammation, and stimulate fibroblasts — the little cells responsible for collagen and elastin production.

Translation: firmer, plumper, healthier-looking skin with fewer lines and better tone.

What areas can be treated?

At Mr. Beautox Aesthetics, I use polynucleotides for:

✨ Under-eye rejuvenation (for those tired or hollow eyes)

✨ Full-face hydration and texture improvement

✨ Neck and décolletage tightening

✨ Acne scarring and redness

✨ Improving general skin quality, glow, and bounce

Is this like a filler or Botox?

Not quite. Polynucleotides don’t freeze muscles like Botox, and they don’t add volume like filler. Instead, they heal and stimulate — improving the structure and quality of your own skin over time.

It’s ideal for anyone who wants natural results, or who isn’t quite ready for traditional injectables.

Does it hurt?

Mild discomfort is possible — especially under the eyes — but most clients say it’s totally manageable. I use numbing cream where needed, and the whole treatment is over in minutes.

How many sessions do I need?

For best results, a course of 2–3 treatments spaced a few weeks apart is ideal, followed by maintenance every few months. You’ll start to notice improvements in hydration and glow quite quickly, with firmer, smoother skin over time.

Is it right for me?

If your skin is looking tired, dull, crepey, or just needs a boost — polynucleotides could be your new best friend. It’s also great for clients who’ve overdone filler in the past and want to “reset” their skin naturally.

Still not sure?

That’s what consultations are for. I’ll talk you through the options, show you what’s possible, and make sure the treatment suits your goals (and your budget).

Just send me a message — I’ll happily answer any questions, even the weird ones.

Ready to book?

 Click here to book online  Or feel free to DM me with any questions.

Written by Rick at Mr. Beautox Aesthetics, Worthing.Qualified. Insured. 100% 5-star reviews. No salmon were harmed in the making of this skin.